logo

        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of diabetic retinopathy (DR)
ncRNA name hsa-miR-1470
ncRNA Category miRNA
Disease name diabetic retinopathy (DR)
Species Homo sapiens
Tissues/Cell_line human retinal endothelial cells (HRECs)
Methods CCK-8 assay, scratch assay, transwell assay, tube formation assay, Western blot, microarray, qRT‐PCR, flow cytometry, luciferase reporter assay
Expression pattern down-regulated
Functional description KCNQ1OT1 level was upregulated while microRNA-1470 (miR-1470) was decreased in DR patients and human retinal endothelial cells. KCNQ1OT1 could sponge miR-1470 and further regulate EGFR in DR.
PubMed ID 30784065
Year 2019
Title KCNQ1OT1 affects the progression of diabetic retinopathy by regulating miR-1470 and epidermal growth factor receptor.
Drug-related ncRNA NO

Copyright © Institution of Biomedical Big Data, Wenzhou Medical University All rights reserved.