ncRNA name | hsa-miR-1470 |
ncRNA Category | miRNA |
Disease name | diabetic retinopathy (DR) |
Species | Homo sapiens |
Tissues/Cell_line | human retinal endothelial cells (HRECs) |
Methods | CCK-8 assay, scratch assay, transwell assay, tube formation assay, Western blot, microarray, qRT‐PCR, flow cytometry, luciferase reporter assay |
Expression pattern | down-regulated |
Functional description | KCNQ1OT1 level was upregulated while microRNA-1470 (miR-1470) was decreased in DR patients and human retinal endothelial cells. KCNQ1OT1 could sponge miR-1470 and further regulate EGFR in DR. |
PubMed ID | 30784065 |
Year | 2019 |
Title | KCNQ1OT1 affects the progression of diabetic retinopathy by regulating miR-1470 and epidermal growth factor receptor. |
Drug-related ncRNA | NO |
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